‘First-in-Human’ Drug for Malignant Glioma Available in Experimental Trial

Blake knew he was in the right hands the moment he saw the surgeon’s wrists. Dr. John M. Tew, Blake’s neurosurgeon, was wearing one of Lance Armstrong’s yellow LiveStrong cancer bracelets. So was Blake. Dr. Tew, who was also sporting a Tour de France lanyard, was an avid cyclist. So was Blake.

Charlene marked her seven-year survivorship of glioblastoma multiforme in March 2012 with two significant events. The first was the return of her tumor, a difficult cancer whose potency can never be overestimated. The second was the successful surgical removal of the recurrent cancer by her University of Cincinnati Brain Tumor Center team.

On an ordinary day in February 2009, John M. Tew, MD, got one of the true surprises of his career. He was seeing patients in his Mayfield Clinic office on the University of Cincinnati medical campus when an unexpected guest arrived. Jerry, a retired law enforcement officer from rural Kentucky, walked into Dr. Tew’s office to say thank you.

John, a retired painter and carpenter, is a tall, solidly built man with a strong inclination toward getting things done. A former Vista volunteer who was equally comfortable running a food co-op in an underserved neighborhood or standing near the top of a tall ladder, he is a natural at lending a hand to people who can’t quite make it on their own.

Sandra (Sandy) is a smiling, breathing reminder that hope exists for patients with even the most challenging type of brain tumors.

Thirteen years ago, when Sandy was first told that she had six months to live, she stared back blankly at her doctor. “Who are they talking about?” she remembers thinking. “That isn’t me. I’m not going anywhere. I was determined to live.”